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1.
Postgrad Med J ; 98(1162): 633-643, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1560889

ABSTRACT

'Post-COVID-19 syndrome' refers to symptoms in the convalescent phase following initial COVID-19 infection. This term encompasses a wide array of presentation involving lungs, heart and the neuromuscular system. Pulmonary manifestations include post-COVID-19 fibrosis, which is akin to post acute respiratory distress syndrome fibrosis and may reflect the permanent damage to the lungs following an initial bout of infection. Cardiovascular system is often involved, and the presentation can be in terms of acute coronary syndrome, myocarditis and heart failure. Clinical manifestations are often varied and non-specific, which entails a detailed workup and a multidisciplinary approach. Post-COVID-19 syndrome adds to the overall disease morbidity and leads to a prolonged hospital stay, greater healthcare utilisation and loss of productivity marring the country's dwindling economy. Thus, it is imperative that post-COVID-19 syndrome be prevented and identified early followed by a prompt treatment.


Subject(s)
Acute Coronary Syndrome , COVID-19 , Myocarditis , COVID-19/complications , Fibrosis , Humans , Myocarditis/diagnosis , Myocarditis/therapy , SARS-CoV-2
2.
Monaldi Arch Chest Dis ; 90(2)2020 May 07.
Article in English | MEDLINE | ID: covidwho-216029

ABSTRACT

A novel coronavirus, SARS-CoV-2, thought to have originated from bats causes COVID-19 infection which was first reported from Wuhan, China in December 2019. This virus has a high infectivity rate and has impacted a significant chunk of the population worldwide. The spectrum of disease ranges from mild to severe with respiratory system being the most commonly affected. Cardiovascular system often gets involved in later stages of the disease with acute cardiac injury, heart failure and arrhythmias being the common complications. In addition, the presence of cardiovascular co-morbidities such as hypertension, coronary artery disease in these patients are often associated with poor prognosis. It is still not clear regarding the exact mechanism explaining cardiovascular system involvement in COVID-19. Multiple theories have been put forward however, more robust studies are required to fully elucidate the "heart and virus" link. The disease has already made its presence felt on the global stage and its impact in the developing countries is going to be profound. These nations not only have a poorly developed healthcare system but there is also a huge burden of cardiovascular diseases. As a result, COVID-19 would adversely impact the already overburdened healthcare network leading to impaired cardiovascular care delivery especially for acute coronary syndrome and heart failure patients.


Subject(s)
Cardiovascular Diseases/complications , Cardiovascular System/virology , Coronavirus Infections/complications , Pneumonia, Viral/complications , Angiotensin-Converting Enzyme Inhibitors/therapeutic use , Arrhythmias, Cardiac/virology , Betacoronavirus , COVID-19 , Cardiovascular Diseases/virology , Comorbidity , Developing Countries , Heart/virology , Heart Transplantation , Humans , Myocarditis/virology , Myocardium/pathology , Pandemics , SARS-CoV-2 , ST Elevation Myocardial Infarction/virology
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